![]() An artificial pancreas (AP) with a closed-loop delivery system with > 95% time in range is believed to soon become a reality. ![]() Popular devices used for insulin administration are syringes, pens, and pumps. The major challenge of insulin despite its efficacy has been the occurrence of hypoglycemia, which has resulted in sub-optimal dosages being prescribed in the vast majority of patients. ![]() Insulin, the first medication to be discovered for diabetes, is still the safest and most potent glucose-lowering therapy. The year 2021 will mark 100 years since the discovery of insulin.
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